Postoperative Clostridium difficile-associated diarrhea
نویسندگان
چکیده
منابع مشابه
Clostridium difficile-associated diarrhea.
At our hospital, the number of cases of Clostridium difficile-associated diarrhoea increased from 29 in 1993 to 210 in 1995. The case notes of 110 patients with C difficile-associated diarrhoea during the first 6 months of 1995 were analysed retrospectively. The majority of the patients (106) had received antibiotics before the onset of diarrhoea; 46 had received three or more different antibio...
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Sir—We read with interest the article by Pépin et al. [1], which reports that use of quinolones is a major risk factor for illness during an outbreak of Clostridium difficile–associated diarrhea (CDAD). These results confirm previous observations that quinolones and other antibiotics, such as third-generation cephalosporins, macrolides, broad-spectrumb-lactams, and aminoglycosides, are importan...
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We performed a case-control study to evaluate the association between antibiotic use and Clostridium difficile-associated diarrhea (CDAD), matching for admission unit and time at risk for CDAD. A multivariable regression model showed that treatment with fluoroquinolones (odds ratio 12.7; 95% confidence interval 2.6 to 61.6) was the strongest risk factor for CDAD.
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Clostridium difficile-associated diarrhea (CDAD) is the most common etiologically-defined cause of hospital-acquired diarrhea. Caused by the toxins of certain strains of C difficile, CDAD represents a growing concern, with epidemic outbreaks in some hospitals where very aggressive and difficult-to-treat strains have recently been found. Incidence of CDAD varies ordinarily between 1 to 10 in eve...
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Clostridium difficile is the most important cause of nosocomial diarrhea in adults. Illness may range from mild watery diarrhea to life-threatening colitis. An antecedent disruption of the normal colonic flora followed by exposure to a toxigenic strain of C. difficile are necessary first steps in the pathogenesis of disease. Diagnosis is based primarily on the detection of C. difficile toxin A ...
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ژورنال
عنوان ژورنال: Surgery
سال: 2010
ISSN: 0039-6060
DOI: 10.1016/j.surg.2009.11.021